Service Line:+1-315-239-3085
Address:FL-4, Building A5, International Enterprise Community, Tianjin, China
Email:info@kmdbioscience.com
Catalog Number | KMP3893 |
---|---|
Product Name | Mouse TNF-alpha Protein |
Product Description | The Mouse TNF-alpha Protein(KMP3893) is produced in E. coli. A DNA sequence encoding the soluble form of Mouse TNF-α (NP_038721.1) (Leu 80-Leu 235) is expressed, with an initial Met at the N-terminus. |
Molecular Name | TNF-alpha |
Alias | TNF-alpha Protein, Mouse TNF-alpha Protein |
Size | 50ug, 100ug, 200ug |
Species | Mouse |
Host | E. coli |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | PBS, pH7.4 |
Purification | Affinity purification |
Molecular Weight | 17.39 kDa |
Background | Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & Antibody |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |