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Catalog Number | KMP3968 |
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Product Name | Mouse PDGF-B Protein, His Tag |
Product Description | The Mouse PDGF-B Protein(KMP3968) is produced in Yeast. A DNA sequence encoding the Mouse PDGFB (AAH23427.1) (Ser82-Thr190) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | PDGF-B |
Alias | PDGF-B Protein, Mouse PDGF-B Protein, His Tag |
Size | 50ug, 100ug, 200ug |
Species | Mouse |
Host | Yeast |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | 30% CAN, 0.1% TFA |
Purification | Affinity purification |
Molecular Weight | 14.2 kDa |
Background | Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |