KMD Bioscience Co., Ltd.
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| Catalog Number | KMP3986 |
|---|---|
| Product Name | Mouse TNFSF13 Protein, hFc Tag |
| Product Description | The Mouse TNFSF13 Protein(KMP3986) is produced in HEK293 Cells. A DNA sequence encoding the Mouse TNFSF13 (Q9D777) (Ala96-Leu240) is expressed with the fused Fc region of human IgG1 at the N-terminus. |
| Molecular Name | TNFSF13 |
| Alias | TNFSF13 Protein, Mouse TNFSF13 Protein, hFc Tag |
| Size | 50ug, 100ug, 200ug |
| Species | Mouse |
| Host | HEK293 Cells |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, pH7.4 |
| Purification | Affinity purification |
| Molecular Weight | 44.8 kDa |
| Background | TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. It is a ligand for TNFRSF17/BCMA. TNFSF13 is lowly expressed in normal tissues, but is elevated in several types of tumors and transformed cell lines. It is important for B cell development. TNFSF13 may also play a role in T-independent type II antigen responses and T cell survival, and induce proliferation/survival of non lymphoid cells. It exists as a functional homotrimer. It can bind to two cell surface receptors, BCMA and TACI, which it shares with BAFF to exert downstream T- and B-cell regulatory effects. TNFSF13 also has been demonstrated to bind to proteoglycans on the cell surface. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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