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Catalog Number | KMP4000 |
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Product Name | Mouse B4GALT1 Protein, His Tag |
Product Description | The Mouse B4GALT1 Protein(KMP4000) is produced in HEK293 Cells. A DNA sequence encoding the Mouse B4GALT1 (P15535) (Gly44-Arg399) is expressed, with a polyhistidine tag at the N-terminus. |
Molecular Name | B4GALT1 |
Alias | B4GALT1 Protein, Mouse B4GALT1 Protein, His Tag |
Size | 50ug, 100ug, 200ug |
Species | Mouse |
Host | HEK293 Cells |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | PBS, pH7.4 |
Purification | Affinity purification |
Molecular Weight | 41.12 kDa |
Background | Beta1,4-Galactosyltransferase-I (B4GALT1), one of seven beta1,4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. They have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. B4GALT1 gene directs production of B4GALT1 protein using either of two transcription start sites. The product of the smaller transcript serves the traditional biosynthetic role in the Golgi. This form also complexes with α-lactalbumin, a mammary-specific protein, to form lactose synthase. In addition to a biosynthetic role, the protein translated from the longer transcript appears on the plasma membranes of some cells where it serves as a signalling receptor in cell-matrix interactions such as sperm-egg binding. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |