KMD Bioscience Co., Ltd.
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| Catalog Number | KMP4140 |
|---|---|
| Product Name | Mouse LRRC32 Protein, hFc Tag |
| Product Description | The Mouse LRRC32 Protein(KMP4140) is produced in HEK293 Cells. A DNA sequence encoding the Mouse LRRC32 (G3XA59) (Met1-Asn628) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | LRRC32 |
| Alias | LRRC32 Protein, Mouse LRRC32 Protein, hFc Tag |
| Size | 50ug, 100ug, 200ug |
| Species | Mouse |
| Host | HEK293 Cells |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, 5% Trehalose, pH7.4 |
| Purification | Affinity purification |
| Molecular Weight | 93.38 kDa |
| Background | LRRC32 (Leucine-Rich Repeat Containing 32) is a Protein Coding gene. This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. LRRC32, also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 is a T(reg)-specific receptor that binds latent TGF-beta and dominantly controls FOXP3 and the regulatory phenotype via a positive feedback loop. It belongs to the LRRC32/LRRC33 family and is broadly expressed in the placenta, lung, and other tissues. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies. An important paralog of this gene is NRROS. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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