Service Line:+1-315-239-3085
Address:FL-4, Building A5, International Enterprise Community, Tianjin, China
Email:info@kmdbioscience.com
Catalog Number | KMP4142 |
---|---|
Product Name | Mouse GPRC5D Protein, Flag Tag |
Product Description | The Mouse GPRC5D Protein(KMP4142) is produced in HEK293 Cells. A DNA sequence encoding the Mouse GPRC5D (Q9JIL6-2) (Met1-Cys300) is expressed. |
Molecular Name | GPRC5D |
Alias | GPRC5D Protein, Mouse GPRC5D Protein, Flag Tag |
Size | 50ug, 100ug, 200ug |
Species | Mouse |
Host | HEK293 Cells |
Purity | >90% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | 50mM Hepes, 150mM NaCl, 10% Trehalose, pH7.2 |
Purification | Affinity purification |
Molecular Weight | 35.8 kDa |
Background | Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |