Rhesus Semaphorin 4D Protein, His Tag

Product Information

Catalog Number	KMP4314
Product Name	Rhesus Semaphorin 4D Protein, His Tag
Product Description	The Rhesus Semaphorin 4D Protein(KMP4314) is produced in HEK293 Cells. A DNA sequence encoding the Rhesus SEMA4D (EHH24221.1) (Met1-Arg734) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	Semaphorin 4D
Alias	Semaphorin 4D Protein, Rhesus Semaphorin 4D Protein, His Tag
Size	50ug, 100ug, 200ug
Species	Rhesus
Host	HEK293 Cells
Purity	>90% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	PBS, pH7.4
Purification	Affinity purification
Molecular Weight	80.7 kDa
Background	Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

Cat#	Product Name	Species	Host	Applications	Size	Price
KMP2931	Human Semaphorin 4D Protein, hFc Tag	Human	HEK293 Cells		50ug, 100ug, 200ug	Inquiry