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Catalog Number | KMP4344 |
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Product Name | Zebrafish EFNB2A Protein, hFc Tag |
Product Description | The Zebrafish EFNB2A Protein(KMP4344) is produced in HEK293 Cells. A DNA sequence encoding the zebrafish EFNB2A (O73874) (Met 1-Ala222) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | EFNB2A |
Alias | EFNB2A Protein, Zebrafish EFNB2A Protein, hFc Tag |
Size | 50ug, 100ug, 200ug |
Species | Zebrafish |
Host | HEK293 Cells |
Purity | >90% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | PBS, pH7.4 |
Purification | Affinity purification |
Molecular Weight | 48.9 kDa |
Background | Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Efnb2a, together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |