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CV (strain G-10) VP1 Protein, Fc Tag

Product Information
Catalog Number KMP4418
Product Name CV (strain G-10) VP1 Protein, Fc Tag
Product Description The CV (strain G-10) VP1 Protein(KMP4418) is produced in Insect Cells. A DNA sequence encoding the VP1 of Coxsackievirus A16 (Cox A16) (strain G-10) (AAA50478.1) (Gly568-Lys862) was expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name CV VP1
Molecular Weight 59.5 kDa
Alias CV VP1, Capsid Protein VP1, CV VP1 Protein
Size 50ug, 100ug, 200ug
Species CV
Host Insect Cells
Purity >90% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer 40mM PB, 500mM NaCl, pH7.4
Purification Affinity purification
Background Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to the formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of the N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.