KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMP4426 |
|---|---|
| Product Name | DENV (type 3, strain Philippines/H87/1956) NS1 Protein, His Tag |
| Product Description | The DENV (type 3, strain Philippines/H87/1956) NS1 Protein(KMP4426) is produced in HEK293 Cells. A DNA sequence encoding the Dengue virus (DENV) (type 3, strain Philippines/H87/1956) NS1 (AAA99437.1) (Asp774-Ala1125) was expressed with a polyhistidine tag at the N-terminus. |
| Molecular Name | DENV NS1 |
| Molecular Weight | 42.1 kDa |
| Alias | DENV NS1, Nonstructural Protein 1, DENV NS1 Protein |
| Size | 50ug, 100ug, 200ug |
| Species | DENV |
| Host | HEK293 Cells |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, pH7.4 |
| Purification | Affinity purification |
| Background | Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent with those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross-reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross-reactivity with dengue and YF. Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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Email：info@kmdbioscience.com
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