KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | MOP2102 |
|---|---|
| Product Name | Recombinant Mouse Clusterin/Clu Protein, His Tag |
| Product Description | Recombinant Mouse Clusterin/Clu Protein, His Tag (MOP2102) contains the mouse Clu(Glu22-Glu448) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | Clu |
| Uniprot ID | Q06890 |
| Alias | Cli, ApoJ, Sgp2, SP 40, Sgp 2, Sugp 2, AI893575, D14Ucla3, Msgp 2, clusterin |
| Protein Family | Other protein |
| Size | 50ug, 100ug |
| Species | Mouse |
| Host | Mammalian cells |
| Molecular Weight | 46.97 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | Clusterin mRNA and Clusterin protein are shown to increase with androgen treatment. Binding of clusterin to the LDL-Receptor plays a role in the pathogenesis of membranous glomerulonephritis. Clusterin is down regulated in CaP in association with matched benign controls. Clusterin is involved in cellular senescence and tumorigenesis. Clusterin is involved in photo-oxidative cell death pathway. Clusterin is a functional tumor marker for the diagnosis of pediatric large cell lymphoma. Clusterin is activated in low pH. Clusterin is involved in the inhibition of NF-kappaB signaling through stabilization of IkappaBs thus results in suppression of tumor cell motility. N-terminal deletion of clusterin is vital for its alterations of biogenesis in esophageal squamous cell carcinoma. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
Technical Support：sales@kmdbiosci.com
