Recombinant Mouse Dr6/Tnfrsf21 Protein, His & Fc Tag

Product Information

Catalog Number	MOP2131
Product Name	Recombinant Mouse Dr6/Tnfrsf21 Protein, His & Fc Tag
Product Description	Recombinant Mouse Dr6/Tnfrsf21 Protein, His & Fc Tag (MOP2131) contains the mouse Tnfrsf21(Gln42-His349) was fused with the C-terminal His, Fc Tag and expressed in Mammalian cells.
Molecular Name	Tnfrsf21
Uniprot ID	Q9EPU5
Alias	DR6, TR7, R74815, AA959878, tumor necrosis factor receptor superfamily, member 21
Protein Family	Other protein
Size	50ug, 100ug
Species	Mouse
Host	Mammalian cells
Molecular Weight	58.88 kDa
Purity	≥90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity	No cross-reactivity with other antigens or proteins.
Buffer	PBS
Purification	Affinity Purification
Background	Death receptor-6 (DR6), a member of the death domain-containing TNFR superfamily, is highly expressed in lymphoid tissues and regulated upon lymphocyte activation. Targeted disruption of DR6 results in enhanced CD4(+) T cell proliferation and T helper 2 differentiation in vitro. DR6 contains an extracellular region and an intracellular region; the intracellular region harbors a death domain that is critical for transduction of apoptotic signals. DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK.
Storage	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.

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