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Catalog Number | MOP2164 |
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Product Name | Recombinant Mouse G-Csf/Csf3r Protein, His Tag |
Product Description | Recombinant Mouse G-Csf/Csf3r Protein, His Tag (MOP2164) contains the mouse Csf3r(Val31-Ala208) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | Csf3r |
Uniprot ID | P40223 |
Alias | Cd114, Csfgr, G CSFR, G CSF R, colony stimulating factor 3 receptor(granulocyte) |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Mouse |
Host | Mammalian cells |
Molecular Weight | 19.58 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Granulocyte Colony Stimulating Factor Receptor (G-CSFR) which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3, a cytokine that plays a critical role in the regulation of the activation, proliferation, differentiation, and survival of the neutrophilic granulocyte lineage. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. G-CSFR mediates the specific effect of G-CSF through activating a variety of intracellular signaling cascades, including the Jak/Stat, PI3/Akt, Ras-Raf-MAP kinase, and Src family kinase pathways, and thus functions in defense against infection, inflammation and repair, and in the maintenance of steady state hematopoiesis. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |