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Anti-Human TGFB1 Recombinant Antibody

Product Information
Catalog Number YR1121
Product Name Anti-Human TGFB1 Recombinant Antibody
Molecular Name Metelimumab
Alias Anti-TGFB1 Recombinant Antibody, Research Grade Metelimumab
CAS Number 272780-74-2
Target TGFB1[Homo sapiens]
Isotype IgG4 Kappa
Clonity Monoclonal
Source CHO Cells
Size 1mg, 5mg
Concentration 1mg/ml
Purity >95% as determined by SDS-PAGE
Applications IF, IP, Neut, FuncS, ELISA, FCM, ICC
Buffer PBS, pH7.5
Background Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that neutralizes TGF beta 1 which had been chosen for further development for the treatment of diffuse cutaneous systemic sclerosis, also known as scleroderma. It was dropped from further development in favour of fresolimumab, which was being developed by Genzyme as of 2006.
Storage It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.