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Catalog Number | YR1121 |
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Product Name | Anti-Human TGFB1 Recombinant Antibody |
Molecular Name | Metelimumab |
Alias | Anti-TGFB1 Recombinant Antibody, Research Grade Metelimumab |
CAS Number | 272780-74-2 |
Target | TGFB1[Homo sapiens] |
Isotype | IgG4 Kappa |
Clonity | Monoclonal |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Applications | IF, IP, Neut, FuncS, ELISA, FCM, ICC |
Buffer | PBS, pH7.5 |
Background | Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that neutralizes TGF beta 1 which had been chosen for further development for the treatment of diffuse cutaneous systemic sclerosis, also known as scleroderma. It was dropped from further development in favour of fresolimumab, which was being developed by Genzyme as of 2006. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |