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Anti-Human CD4 D3 Domain Recombinant Antibody

Product Information
Catalog Number YR1157
Product Name Anti-Human CD4 D3 Domain Recombinant Antibody
Molecular Name Ibalizumab
Alias Anti-CD4 D3 Domain Recombinant Antibody, Research Grade Ibalizumab
CAS Number 680188-33-4
Target CD4 D3 domain[Homo sapiens]
Isotype IgG4 Kappa
Clonity Monoclonal
Host Mouse
Source CHO Cells
Size 1mg, 5mg
Concentration 1mg/ml
Purity >95% as determined by SDS-PAGE
Applications FuncS, IF, Neut, ELISA, FCM, IP, ICC
Buffer PBS, pH7.5
Background Ibalizumab (trade name Trogarzo) is a non-immunosuppressive humanised monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits HIV from entering cells. It is a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4 cell.
Storage It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.