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Catalog Number | YR1157 |
---|---|
Product Name | Anti-Human CD4 D3 Domain Recombinant Antibody |
Molecular Name | Ibalizumab |
Alias | Anti-CD4 D3 Domain Recombinant Antibody, Research Grade Ibalizumab |
CAS Number | 680188-33-4 |
Target | CD4 D3 domain[Homo sapiens] |
Isotype | IgG4 Kappa |
Clonity | Monoclonal |
Host | Mouse |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Applications | FuncS, IF, Neut, ELISA, FCM, IP, ICC |
Buffer | PBS, pH7.5 |
Background | Ibalizumab (trade name Trogarzo) is a non-immunosuppressive humanised monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits HIV from entering cells. It is a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4 cell. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |