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Catalog Number | YR1222 |
---|---|
Product Name | Anti-Human CA9 Recombinant Antibody |
Molecular Name | Girentuximab |
Alias | Anti-CA9 Recombinant Antibody, Research Grade Girentuximab |
CAS Number | 916138-87-9 |
Target | CA9[Homo sapiens] |
Isotype | IgG1 Kappa |
Clonity | Monoclonal |
Host | Mouse |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Applications | WB, FuncS, IF, Neut, ELISA, FCM, IP, PK, IHC, Activ |
Buffer | PBS, pH7.5 |
Background | Girentuximab (trade name Rencarex) is a chimeric IgG1 monoclonal antibody to carbonic anhydrase IX (CAIX). CAIX is expressed on the surface of most renal cancer cells and is hypothesized to be on the surface of other tumor cells. It is investigational agent in clinical trials for renal cell carcinoma. Its development was suspended as a "naked" or unconjugated antibody during phase III trials due to efficacy. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |