Anti-Human GPNMB Extracellular Domain Recombinant Antibody

Product Information

Catalog Number	YR1224
Product Name	Anti-Human GPNMB Extracellular Domain Recombinant Antibody
Molecular Name	Glembatumumab
Alias	Anti-GPNMB Extracellular Domain Recombinant Antibody, Research Grade Glembatumumab
CAS Number	1020264-78-1
Target	GPNMB extracellular domain[Homo sapiens]
Isotype	IgG2 Kappa
Clonity	Monoclonal
Source	CHO Cells
Size	1mg, 5mg
Concentration	1mg/ml
Purity	>95% as determined by SDS-PAGE
Buffer	PBS, pH7.5
Background	Glembatumumab vedotin (also known as CDX-011 and CR011-vcMMAE) is an antibody-drug conjugate (ADC) that targets cancer cells expressing transmembrane glycoprotein NMB (GPNMB). In May 2010, the U.S FDA granted Fast Track designation to CDX-011 for the treatment of advanced, refractory, or resistant GPNMB-expressing breast cancer.
Storage	It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

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