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Catalog Number | YR1277 |
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Product Name | Anti-Human ERBB3 Recombinant Antibody(Duligotuzumab) |
Molecular Name | Duligotuzumab |
Alias | Anti-ERBB3 Recombinant Antibody, Research Grade Duligotuzumab |
CAS Number | 1314238-96-4 |
Target | ERBB3[Homo sapiens] |
Isotype | IgG1 Kappa |
Clonity | Monoclonal |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Applications | FCM, IP, ELISA, Neut, FuncS, IF, WB |
Buffer | PBS, pH7.5 |
Background | Duligotuzumab (INN) is a humanized IgG1 monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to HER3. It is in development by Roche. Clinical development for head and neck cancer and colorectal cancer have been discontinued, but phase I trials in combination with cobimetinib are evaluating safety for treatment of solid tumors. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |