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Anti-Human ERBB3 Recombinant Antibody(Duligotuzumab)

Product Information
Catalog Number YR1277
Product Name Anti-Human ERBB3 Recombinant Antibody(Duligotuzumab)
Molecular Name Duligotuzumab
Alias Anti-ERBB3 Recombinant Antibody, Research Grade Duligotuzumab
CAS Number 1314238-96-4
Target ERBB3[Homo sapiens]
Isotype IgG1 Kappa
Clonity Monoclonal
Source CHO Cells
Size 1mg, 5mg
Concentration 1mg/ml
Purity >95% as determined by SDS-PAGE
Applications FCM, IP, ELISA, Neut, FuncS, IF, WB
Buffer PBS, pH7.5
Background Duligotuzumab (INN) is a humanized IgG1 monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to HER3. It is in development by Roche. Clinical development for head and neck cancer and colorectal cancer have been discontinued, but phase I trials in combination with cobimetinib are evaluating safety for treatment of solid tumors.
Storage It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.