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Catalog Number | YR1298 |
---|---|
Product Name | Anti-Human CD279 Recombinant Antibody(Pidilizumab) |
Molecular Name | Pidilizumab |
Alias | Anti-CD279 Recombinant Antibody, Research Grade Pidilizumab |
CAS Number | 1036730-42-3 |
Target | CD279[Homo sapiens] |
Isotype | IgG1 Kappa |
Clonity | Monoclonal |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Buffer | PBS, pH7.5 |
Background | Pidilizumab (formerly CT-011) is a monoclonal antibody being developed by Medivation for the treatment of cancer and infectious diseases. Pidilizumab was originally thought to bind to the PD-1 immune checkpoint molecule, however, recent evidence suggests that Delta-like 1 (DLL1) is its primary binding target while binding to PD-1 is secondary and restricted to non-glycosylated and hypoglycosylated forms of this molecule. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |