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Catalog Number | YR1332 |
---|---|
Product Name | Anti-Human CD248 Recombinant Antibody |
Molecular Name | Ontuxizumab |
Alias | Anti-CD248 Recombinant Antibody, Research Grade Ontuxizumab |
CAS Number | 946415-62-9 |
Target | CD248[Homo sapiens] |
Isotype | IgG1 Kappa |
Clonity | Monoclonal |
Host | Mouse |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Applications | Neut, ELISA, IF, IP, FuncS, FCM, ICC |
Buffer | PBS, pH7.5 |
Background | Ontuxizumab is a humanized rabbit monoclonal antibody designed for the treatment of cancer. It binds to endosialin (TEM1 or CD248). Phase I trials are complete and the drug was granted orphan drug status by the FDA for sarcoma. It is currently in phase II trials for melanoma, colorectal cancer, sarcoma, and lymphoma. This drug was developed by Morphotek and Ludwig Institute for Cancer Research. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |