Anti-Human LAG3 Recombinant Antibody

Product Information

Catalog Number	YR1554
Product Name	Anti-Human LAG3 Recombinant Antibody
Molecular Name	Ieramilimab
Alias	Anti-LAG3 Recombinant Antibody, Research Grade Ieramilimab
CAS Number	2137049-37-5
Target	LAG3[Homo sapiens]
Isotype	IgG4 Kappa
Clonity	Monoclonal
Source	CHO Cells
Size	1mg, 5mg
Concentration	1mg/ml
Purity	>95% as determined by SDS-PAGE
Buffer	PBS, pH7.5
Background	Ieramilimab (development code LAG525) is a monoclonal antibody being developed by Novartis for the treatment of cancer. The antibody targets the immune checkpoint LAG-3, which is expressed on T cells and tends to down-regulate an immune response. In a June 2015 presentation Novartis management indicated that 'dosing is imminent' for the first clinical trials of LAG525.
Storage	It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

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