KMD Bioscience Co., Ltd.
400-621-6806
2024-01-23 Hits(293)
In the development and application of in vitro diagnostic reagents, gastric functional target diagnostic materials are important tools for evaluating and monitoring gastric health status. These targets include gastrin-17 (G-17), serum pepsinogen I/II (PGI/II), and Helicobacter pylori (H. pylori) antigens. At present, these raw materials can be widely used in colloidal gold and chemiluminescent platforms, with high sensitivity, high purity, long-term preservation and other characteristics:
Gastrin-17 is a gastrointestinal hormone that is secreted by the G cells of the gastric mucosa and stimulates the secretion of stomach acid. The change of G-17 concentration can reflect the functional state of gastric acid secretion. G-17 is usually tested using techniques such as enzyme-linked immunosorbent assay (ELISA) or radioimmunoassay (RIA) to assess gastric secretory function.
Serum pepsinogen I/II (PGI/II)
The mechanism of action of serum pepsinogen I/II (PGI/II) : Serum pepsinogen I/II is a precursor protein secreted by gastric mucosal cells, which can be converted into pepsin and participate in the digestion process of proteins. The change of PGI/II ratio and concentration is an important index to evaluate the structure and function of gastric mucosa. These raw materials are tested by immunoassay methods such as ELISA and chemiluminescent immunoassay (CLIA), which play a key role in the diagnosis and management of stomach diseases.
Helicobacter pylori (H. pylori)
H. pylori is a bacterium that can infect the gastric mucosa and is associated with a variety of stomach diseases. It affects the secretion of gastric acid and the integrity of gastric mucosa by regulating gastric mucosal cells. Application platform for Helicobacter pylori: H. pylori's diagnostic raw materials include antigen and antibody detection reagents, which can be detected by ELISA, immunochromatography (such as rapid strip tests) and breath tests for the diagnosis of infection.
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KMD Bioscience's diagnostic raw materials come from our company's mature platform for protein expression production and antibody customization service. Based on the perfect expression system and antibody preparation scheme, the company not only provides customers with highly sensitive diagnostic raw materials, but also can customize the production of related proteins and antibodies according to customer needs. For more information, please click:
Diagnosis of raw materials more technical resources, please visit: https://www.kmdbioscience.cn/articles/jishuzhichi.html
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