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Catalog Number | KMH1038 |
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Product Name | Recombinant Human EPHB2 Protein, Fc Tag |
Product Description | Recombinant Human EPHB2 Protein, Fc Tag (KMH1038) contains the human EPHB2(Val19-Ser482) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
Molecular Name | EPHB2 |
Uniprot ID | P29323 |
Alias | DRT, EK5, ERK, CAPB, Hek5, PCBC, EPHT3, Tyro5, BDPLT22, EPH receptor B2 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 76.04 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | EPHB2 is a member of the Eph family of receptor tyrosine kinases that mediate neurodevelopmental processes such as boundary formation, axon guidance, vasculogenesis, and cell migration. EPHB2 has been shown to associate with the non-receptor tyrosine kinase Abl and activated EPHB2 causes tyrosine phosphorylation of Abl and regulates its activity. EPHB2 is overexressed in a number of tumors particularly glioblastoma and this increases glioma cell migration and invasion. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |