KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMH1330 |
|---|---|
| Product Name | Recombinant Human LCP2 Protein, His Tag |
| Product Description | Recombinant Human LCP2 Protein, His Tag (KMH1330) contains the human LCP2(Met1-Pro533) was fused with the C-terminal His Tag and expressed in E. coli. |
| Molecular Name | LCP2 |
| Uniprot ID | Q13094 |
| Alias | SLP76, SLP 76, lymphocyte cytosolic protein 2 |
| Protein Family | Other protein |
| Size | 50ug, 100ug |
| Species | Human |
| Host | E. coli |
| Molecular Weight | 58.63 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | Please contact our customer service for more information. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | SLP-76 was originally identified as a substrate of the ZAP-7 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
Technical Support：sales@kmdbiosci.com
