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Catalog Number | KMH1423 |
---|---|
Product Name | Recombinant Human Myocilin/MYOC Protein, His Tag |
Product Description | Recombinant Human Myocilin/MYOC Protein, His Tag (KMH1423) contains the human MYOC(Ile227-Met504) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | MYOC |
Uniprot ID | Q99972 |
Alias | GPOA, JOAG, TIGR, GLC1A, JOAG1, myocilin |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 30.69 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |