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Recombinant Human Myocilin/MYOC Protein, His Tag

Product Information
Catalog Number KMH1423
Product Name Recombinant Human Myocilin/MYOC Protein, His Tag
Product Description Recombinant Human Myocilin/MYOC Protein, His Tag (KMH1423) contains the human MYOC(Ile227-Met504) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name MYOC
Uniprot ID Q99972
Alias GPOA, JOAG, TIGR, GLC1A, JOAG1, myocilin
Protein Family Other protein
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 30.69 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.