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Catalog Number | KMH1482 |
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Product Name | Recombinant Human NTRK2 Protein, His Tag |
Product Description | Recombinant Human NTRK2 Protein, His Tag (KMH1482) contains the human NTRK2(Cys32-His430) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | NTRK2 |
Uniprot ID | Q16620 |
Alias | OBHD, TRKB, trk B, EIEE58, GP145 TrkB, neurotrophic receptor tyrosine kinase 2 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 43.89 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TRKB is the high affinity catalytic receptor for several neurotrophins, which are small protein growth factors that induce the survival and differentiation of distinct cell populations. TRKB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through TRKB leads to cell differentiation. Mutations in the TRKB gene have been associated with obesity and mood disorders. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |