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Recombinant Human SOST Protein, His Tag

Product Information
Catalog Number KMH1739
Product Name Recombinant Human SOST Protein, His Tag
Product Description Recombinant Human SOST Protein, His Tag (KMH1739) contains the human SOST(Gln24-Tyr213) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name SOST
Uniprot ID Q9BQB4
Alias CDD, VBCH, DAND6, SOST1, sclerostin
Protein Family Other protein
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 20.9 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.