Human SOST Protein, His Tag

Product Information

Catalog Number	KMP2660
Product Name	Human SOST Protein, His Tag
Product Description	The Human SOST Protein(KMP2660) is produced in HEK293 Cells. The target gene encoding the SOST (NP_079513.1) (Gln24-Tyr213) is expressed with a polyhistidine tag at the N-terminus. The purified protein is biotinylated in vitro.
Molecular Name	SOST
Alias	Human SOST Protein, His Tag, SOST
Molecular Weight	22.5 kDa
Species	Human
Size	50ug, 100ug, 200ug
Host	HEK293 Cells
Purity	>90% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	PBS
Purification	Affinity purification
Background	Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteeoblasts differentiated for 21 days, and was originally identified as an important regulator of bone remodeling, homeostasis, and links bone resorption and bone apposition. Recent studies have revealed that Sclerostin protein inhibits the bone growth probably by binding to the extracellular domain of the Wnt coreceptors LRP5 and LRP6 and disrupting Wnt-induced Frizzled-LRP complex formation.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

Cat#	Product Name	Species	Host	Size	Price
KMPH2212	Human SOST Protein, His Tag	Human	HEK293 Cells	20ug, 50ug	Inquiry
PR162	Rat SOST Protein, His Tag	Rat	HEK293 Cells	20ug, 50ug	Inquiry
KMPH5987	Human SOST Protein, His Tag	Human	HEK293 Cells	20ug, 50ug	Inquiry
KMH1739	Recombinant Human SOST Protein, His Tag	Human	Mammalian cells	50ug, 100ug	Inquiry
PA16390	Rabbit Anti-Human SOST pAb	Human	Rabbit	50μl, 100μl	Inquiry