KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMH1741 |
|---|---|
| Product Name | Recombinant Human SPARC Protein, His Tag |
| Product Description | Recombinant Human SPARC Protein, His Tag (KMH1741) contains the human SPARC(Ala18-Ile303) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | SPARC |
| Uniprot ID | P09486 |
| Alias | ON, ONT, OI17, BM 40, secreted protein acidic and cysteine rich |
| Protein Family | Other protein |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 31.46 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | SPARC, an acronym for secreted protein, acidic and rich in cysteine, is also known as osteonectin or BM-4. It is the founding member of a family of secreted matricellular proteins with similar domain structure. The 33 amino acid, 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
