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Recombinant Human SPARC Protein, His Tag

Product Information
Catalog Number KMH1741
Product Name Recombinant Human SPARC Protein, His Tag
Product Description Recombinant Human SPARC Protein, His Tag (KMH1741) contains the human SPARC(Ala18-Ile303) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name SPARC
Uniprot ID P09486
Alias ON, ONT, OI17, BM 40, secreted protein acidic and cysteine rich
Protein Family Other protein
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 31.46 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background SPARC, an acronym for secreted protein, acidic and rich in cysteine, is also known as osteonectin or BM-4. It is the founding member of a family of secreted matricellular proteins with similar domain structure. The 33 amino acid, 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.