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Recombinant Human CD95/FAS Protein, His Tag

Product Information
Catalog Number KMH268
Product Name Recombinant Human CD95/FAS Protein, His Tag
Product Description Recombinant Human CD95/FAS Protein, His Tag (KMH268) contains the human FAS(Met1-Asn173) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name FAS
Uniprot ID P25445
Alias APT1, CD95, FAS1, APO 1, FASTM, ALPS1A, TNFRSF6, Fas cell surface death receptor
Protein Family CD molecule
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 20.22 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS, pH7.5
Purification Affinity Purification
Background Apo-1 (Fas/CD95) is a 45 kD type I transmembrane protein belonging to the TNF receptor family. A subgroup of this receptor family called death receptors, contain 3-4 cysteine-rich repeats in the extracellular portion and a cystoplasmic motif called the death domain, which is responsible for the transduction of the death signal. The death domain associates with FADD/MORT, which in turn connects to aspartate-specific proteases (Caspases) that are implicated as mediators of most types of apoptotic cell death.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.