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Catalog Number | KMH268 |
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Product Name | Recombinant Human CD95/FAS Protein, His Tag |
Product Description | Recombinant Human CD95/FAS Protein, His Tag (KMH268) contains the human FAS(Met1-Asn173) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | FAS |
Uniprot ID | P25445 |
Alias | APT1, CD95, FAS1, APO 1, FASTM, ALPS1A, TNFRSF6, Fas cell surface death receptor |
Protein Family | CD molecule |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 20.22 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS, pH7.5 |
Purification | Affinity Purification |
Background | Apo-1 (Fas/CD95) is a 45 kD type I transmembrane protein belonging to the TNF receptor family. A subgroup of this receptor family called death receptors, contain 3-4 cysteine-rich repeats in the extracellular portion and a cystoplasmic motif called the death domain, which is responsible for the transduction of the death signal. The death domain associates with FADD/MORT, which in turn connects to aspartate-specific proteases (Caspases) that are implicated as mediators of most types of apoptotic cell death. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |