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Catalog Number | KMH303 |
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Product Name | Recombinant Human CD126/IL6R Protein, His Tag |
Product Description | Recombinant Human CD126/IL6R Protein, His Tag (KMH303) contains the human IL6R(Met1-Pro365) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | IL6R |
Uniprot ID | P08887 |
Alias | IL6Q, gp80, CD126, IL6RA, IL6RQ, IL 6RA, IL 6R 1, interleukin 6 receptor |
Protein Family | CD molecule |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 39.44 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | Supplied as solution form in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl./Lyophilized from 50 mM Tris-HCl, pH 7.5, 150 mM NaCl. |
Purification | Affinity Purification |
Background | IL-6 mediates its biological effects through the type I IL-6 receptor system that consists of two chains, IL-6R alpha and gp13. The IL-6R alpha chain is the binding component specific to IL-6; while the gp13 only transmits signals of IL-6 when bound to IL-6R alpha. The gp13 also can transmit signals from LIF, OSM, CNTF, IL-11 and CT-1 in conjunction with other receptor subunits. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |