Recombinant Human CD178/FASLG Protein, His Tag

Product Information

Catalog Number	KMH360
Product Name	Recombinant Human CD178/FASLG Protein, His Tag
Product Description	Recombinant Human CD178/FASLG Protein, His Tag (KMH360) contains the human FASLG(Pro134-Leu281) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name	FASLG
Uniprot ID	P48023
Alias	APTL, FASL, CD178, CD95L, ALPS1B, CD95 L, TNFSF6, TNLG1A, APT1LG1, Fas ligand
Protein Family	CD molecule
Size	50ug, 100ug
Species	Human
Host	Mammalian cells
Molecular Weight	16.28 kDa
Purity	≥90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity	No cross-reactivity with other antigens or proteins.
Buffer	PBS
Purification	Affinity Purification
Background	Fas ligand (FasL) is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Fas ligand is a homotrimeric protein and signals through trimerization of FasR, which spans the membrane of the target cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external serine matrix metalloproteinase MMP-7. Soluble FasL is less active than their membrane-bound counterparts and do not induce receptor trimerization and DISC formation. FasL is regarded as a potential target for immunotherapy.
Storage	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.

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