KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMH366 |
|---|---|
| Product Name | Recombinant Human CD202B/TEK Protein, His Tag |
| Product Description | Recombinant Human CD202B/TEK Protein, His Tag (KMH366) contains the human TEK(Met1-Lys745) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | TEK |
| Uniprot ID | Q02763 |
| Alias | TIE2, VMCM, GLC3E, TIE 2, VMCM1, CD202B, TEK receptor tyrosine kinase |
| Protein Family | CD molecule |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 81.95 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | The molecularweight of the dimer is 25 kDa. The soluble receptor protein consists of thefull extracellular domain (Met1-Val73). TIE-1 (tyrosine kinase with Ig andEGF homology domains 1) and TIE2/TEK comprise a receptor tyrosine kinase(RTK) subfamily with unique structural characteristics: twoimmunoglobulin-like domains flanking three epidermal growth factor (EGF)-likedomains and followed by three fibronectin type III-like repeats in theextracellular region and a split tyrosine kinase domain in the cytoplasmicregion. These receptors are expressed primarily on endothelial andhematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE2 cDNA encodes a 1124 amino acidresidue precursor protein with an 18 residue putative signal peptide, a 727residue extracellular domain and a 354 residue cytoplasmic domain. Twoligands, angiopoietin 1 and angiopoietin 2, which bind TIE2 withhigh-affinity have been identified. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
