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Catalog Number | KMH375 |
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Product Name | Recombinant Human CDW210B/IL10RB Protein, His Tag |
Product Description | Recombinant Human CDW210B/IL10RB Protein, His Tag (KMH375) contains the human IL10RB(Met1-Ser220) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | IL10RB |
Uniprot ID | Q08334 |
Alias | CRFB4, CRF2 4, D21S58, D21S66, CDW210B, IL 10R2, interleukin 10 receptor subunit beta |
Protein Family | CD molecule |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 24.2 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | The functional IL-1 receptor consists of two polypeptide chains, a ligand binding chain IL-1 Rα (IL-1 R1) and a signal transduction molecule known as IL-1 Rβ (IL-1 R2). Both chains of the IL-1 R are expressed on many hematopoietic cells, including lymphocytes, monocytes and neutrophils, with the IL-1 Rβ chain expressed at higher levels than the IL-1 Rα chain in most cases. Interleukin 1 receptor beta (IL-1 Rβ), also known as CD21b and CRF2-4, is an 8-85 kDa member of the type II cytokine receptor family of proteins and contains two fibronectin type-III domains. The widely expressed IL-1 Rβ serves as a signal transducing accessory chain not only for IL-1, but also for other interleukins including IL-22, -28A, -28B and -29 (plus IL-26 in human) when complexed to the ligand-binding chains. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |