KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMH378 |
|---|---|
| Product Name | Recombinant Human CD213A2/IL13RA2 Protein, Fc Tag |
| Product Description | Recombinant Human CD213A2/IL13RA2 Protein, Fc Tag (KMH378) contains the human IL13RA2(Met1-Leu342) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
| Molecular Name | IL13RA2 |
| Uniprot ID | Q14627 |
| Alias | CT19, IL 13R, IL13BP, CD213A2, interleukin 13 receptor subunit alpha 2 |
| Protein Family | CD molecule |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 62.62 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | Interleukin 13 receptor alpha 2, also known as IL13RA2 and CD213A2, binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. IL13RA2 serves as a dominant negative inhibitor or a decoy receptor for IL-13. IL-13Ralpha2 is a promising target for ovarian cancer therapy, and the soluble form of IL-13R may be a possible surrogate marker for disease monitoring. IL13RA2 signaling during prolonged inflammation is also an important therapeutic target for the prevention of TGF-beta(1)-mediated fibrosis. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
