KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMH421 |
|---|---|
| Product Name | Recombinant Human CD272/BTLA Protein, His Tag |
| Product Description | Recombinant Human CD272/BTLA Protein, His Tag (KMH421) contains the human BTLA(Met1-Ser150) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | BTLA |
| Uniprot ID | Q7Z6A9 |
| Alias | BTLA1, CD272, B and T lymphocyte associated |
| Protein Family | CD molecule |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 14.68 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | Supplied as solution form in 50 mM Tris-HCl, pH 8.0, 150 mM NaCl./Lyophilized from 50 mM Tris-HCl, pH 8.0, 150 mM NaCl. |
| Purification | Affinity Purification |
| Background | BTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
