Service Line:+1-315-239-3085
Address:FL-4, Building A5, International Enterprise Community, Tianjin, China
Email:info@kmdbioscience.com
Catalog Number | KMH566 |
---|---|
Product Name | Recombinant Human EGF Protein, His Tag |
Product Description | Recombinant Human EGF Protein, His Tag (KMH566) contains the human EGF(Asn971-Arg1023) was fused with the C-terminal His Tag and expressed in Yeast. |
Molecular Name | EGF |
Uniprot ID | P01133 |
Alias | URG, HOMG4, epidermal growth factor |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Yeast |
Molecular Weight | 7.02 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | Please contact our customer service for more information. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | Supplied as solution form in TBS, pH 7.5./Lyophilized from TBS, pH 7.5. |
Purification | Affinity Purification |
Background | Human epidermal growth factor (EGF) exerts actions on a wide variety of biological processes, and plays an important role in the regulation of cell growth, proliferation, and differentiation mediated by its high-affinity receptor EGFR on the cell surface. It induces differentiation of specific cells, promotes angiogenesis, and inhibits gastric acid secretion in vivo, while serves as a potent mitogenic actor for a variety of cultured cells of both ectodermal and mesodermal origin. Human EGF was originally isolated from urine based on its inhibitory effect on gastric secretion and named urogastrone accordingly. EGF is the founding member of the EGF-family of proteins which are characterized by the presence of at least one EGF structural unit (a conserved 6 cysteine motif that forms three disulfide bonds). The EGF precursor is believed to exist as a membrane-bound molecule containing 9 EGF units, and is proteolytically cleaved to generate the 53-amino acid peptide hormone. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |