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Catalog Number | KMH687 |
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Product Name | Recombinant Human ApolipoProtein E/APOE Protein, His Tag |
Product Description | Recombinant Human ApolipoProtein E/APOE Protein, His Tag (KMH687) contains the human APOE(Glu19-Gln311) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | APOE |
Uniprot ID | P08226 |
Alias | AD2, LPG, APO E, ApoE4, LDLCQ5, apolipoprotein E |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 32.23 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |