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Cynomolgus TNFRSF17 Protein, His Tag

Product Information
Catalog Number KMP2241
Product Name Cynomolgus TNFRSF17 Protein, His Tag
Product Description The Cynomolgus TNFRSF17 Protein(KMP2241) is produced in HEK293 Cells and the target gene encoding Met1-Ala53 is expressed with a 6His tag at the C-terminus.
Molecular Weight 6.49 kDa
Alias CD269, BCMA
Species Cynomolgus
Host HEK293 Cells
Size 50ug, 100ug, 200ug
Purification Affinity purification
Purity >85% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer 50mM Tris, 100mM Glycine, pH7.5
Uniprot A0A2K5UD97
SDS-PAGE
Background B cell maturation antigen(BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development,function and regulation.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.