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Rhesus Macaque CD160 Protein, Fc Tag

Product Information
Catalog Number KMP2292
Product Name Rhesus Macaque CD160 Protein, Fc Tag
Product Description The Rhesus Macaque CD160 Protein(KMP2292) is produced in HEK293 Cells and the target gene encoding Met1-Leu158 is expressed with a Fc tag at the C-terminus.
Molecular Weight 17.38 kDa
Alias CD160 antigen, CD160
Species Rhesus Macaque
Host HEK293 Cells
Size 50ug, 100ug, 200ug
Purification Affinity purification
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Uniprot G7MG20
SDS-PAGE
Background CD160 antigen is a cell membrane protein which contains one Ig-likeV-type(immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.