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Rhesus Macaque VTCN1 Protein

Product Information
Catalog Number KMP2293
Product Name Rhesus Macaque VTCN1 Protein
Product Description The Rhesus Macaque VTCN1 Protein(KMP2293) is produced in HEK293 Cells and the target gene encoding Phe29-Ala258 is expressed
Molecular Weight 25.3 kDa
Alias T cell costimulatory molecule B7x, VTCN1
Species Rhesus Macaque
Host HEK293 Cells
Size 50ug, 100ug, 200ug
Purification Affinity purification
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Uniprot F7B770
SDS-PAGE
Background B7 Homolog 4(B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells(Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.