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Mouse CD48 Protein, His Tag

Product Information
Catalog Number KMP2311
Product Name Mouse CD48 Protein, His Tag
Product Description The Mouse CD48 Protein(KMP2311) is produced in HEK293 Cells and the target gene encoding Phe23-Arg216 is expressed with a 6His tag at the C-terminus.
Molecular Weight 22 kDa
Alias SLAM Family Member 2, CD48
Species Mouse
Host HEK293 Cells
Size 50ug, 100ug, 200ug
Purification Affinity purification
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Uniprot Q18PH8
SDS-PAGE
Background CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. Among dendritic cells(DC), CD48 is selectively expressed on circulating myeloid DC and resident bone marrow and thymus DC. CD2, 2B4, and heparan sulfate function as CD48 ligands. CD48 is competent to transduce signals and can also trigger signaling through CD2 or 2B4. CD48 expressed on NK cells is coactivating, whereas CD48 expressed on other cell types inhibits NK cell activation.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.