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Human CD70 Protein, Fc Tag

Product Information
Catalog Number KMP2377
Product Name Human CD70 Protein, Fc Tag
Product Description The Human CD70 Protein(KMP2377) is produced in HEK293 Cells and the target gene encoding Gln45-Pro193 is expressed with a Fc tag at the C-terminus.
Molecular Weight 16.44 kDa
Alias Tumor necrosis factor ligand superfamily member 7, CD70
Species Human
Host HEK293 Cells
Size 50ug, 100ug, 200ug
Purification Affinity purification
Purity >90% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Uniprot M0QZW2
SDS-PAGE
Background CD27 Ligand(CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor(TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.