Macaca Fascicularis CD223 Protein, His Tag

Product Information

Catalog Number	KMP2389
Product Name	Macaca Fascicularis CD223 Protein, His Tag
Product Description	The Macaca Fascicularis CD233 Protein(KMP2389) is produced in HEK293 Cells and the target gene encoding Ala18-Leu450 is expressed with a 8His tag at the N-terminus.
Molecular Weight	48.18 kDa
Alias	Lymphocyte activation gene 3 protein, LAG3
Species	Macaca Fascicularis
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purification	Affinity purification
Purity	>90% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	PBS, pH7.4
Background	Lymphocyte Activating 3(LAG3) belongs to immunoglobulin(Ig) superfamily, Macaca fascicularis LAG3 cDNA encodes 533 amino acids(aa) that include a 17 aa signal sequence, a 451 aa extracellular domain(ECD) with two Ig-like domains, a transmembrane region and a highly charged cytoplasmic region. LAG3's main ligand is MHC class II, to which it binds with higher affinity than CD4.The protein negatively regulates cellular proliferation, activation, and homeostasis of T cells, in a similar fashion to CTLA-4 and PD-1 and has been reported to play a role in Treg suppressive function.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

Cat#	Product Name	Species	Host	Size	Price
KMP2247	Human CD223 Protein, His Tag, Avi Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2285	Human CD223 Protein, mFc Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2341	Mouse CD223 Protein, His Tag	Mouse	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2363	Human CD223 Protein, His Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2400	Cynomolgus CD223 Protein, Fc Tag	Cynomolgus	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2427	Human CD223 Protein, His Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2428	Human CD223 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry