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| Catalog Number | KMP2411 |
|---|---|
| Product Name | Human CD27 Protein, Fc Tag, His Tag |
| Product Description | The Human CD27 Protein(KMP2411) is produced in HEK293 Cells and the target gene encoding Thr21-Ile192 is expressed with a Fc, 6His tag at the C-terminus. |
| Molecular Weight | 20.08 kDa |
| Alias | CD27 antigen, CD27L receptor, T-cell activation antigen CD27 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purification | Affinity purification |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | 20mM Tris, 150mM NaCl, pH8.0 |
| Uniprot | P26842 |
| Function | Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
| Background | CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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