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Human CD40L Receptor Protein, His Tag

Product Information
Catalog Number KMP2431
Product Name Human CD40L Receptor Protein, His Tag
Product Description The Human CD40L Receptor Protein(KMP2431) is produced in HEK293 Cells and the target gene encoding Glu21-Arg193 is expressed with a 6His tag at the C-terminus.
Molecular Weight 19.99 kDa
Alias Tumor Necrosis Factor Receptor Superfamily member 5, CD40L
Species Human
Host HEK293 Cells
Size 50ug, 100ug, 200ug
Purification Affinity purification
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Uniprot A0A8Q3WKP3
SDS-PAGE
Background CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand(CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins(adaptor proteins) have been identified to serves as mediators of the signal transduction.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.