Human CXCL17 Protein, His Tag

Product Information

Catalog Number	KMP2762
Product Name	Human CXCL17 Protein, His Tag
Product Description	The Human CXCL17 Protein(KMP2762) is produced in Yeast. The target gene encoding the human CXCL17 (NP_940879.1) (Leu24-Leu119) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	CXCL17
Alias	Human CXCL17 Protein, His Tag, CXCL17
Molecular Weight	12.7 kDa
Species	Human
Size	50ug, 100ug, 200ug
Host	Yeast
Purity	>90% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	PBS, pH7.4
Purification	Affinity purification
Background	Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with breast cancer, and can promote proliferation and migration of breast cancer cells in vitro and in vivo. CXCL17 is expressed in a variety of cancers and promotes tumor progression by recruiting myeloid-derived suppressor cells (MDSCs). CXCL17 attenuates IMQ-induced psoriasis-like skin inflammation by recruiting MDSCs and Tregs, which may be important for regulating excessive inflammation in psoriasis skin. CXCL17 production correlated with adverse immune infiltration and might be an important target for anti-HCC therapies. CXCL17 is a major regulator of mucosal inflammatory responses.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

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