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Human KIR2DL3 Protein, hFc Tag

Product Information
Catalog Number KMP3021
Product Name Human KIR2DL3 Protein, hFc Tag
Product Description The Human KIR2DL3 Protein(KMP3021) is produced in HEK293 Cells. The target gene encoding the human KIR2DL3 (AAX23102.1) (Met1-His245) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name KIR2DL3
Alias Human KIR2DL3 Protein, hFc Tag, KIR2DL3
Molecular Weight 51.6 kDa
Species Human
Size 50ug, 100ug, 200ug
Host HEK293 Cells
Purity >90% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Background Killer cell immunoglobulin-like receptor 2DL3, also known as CD158 antigen-like family member B2, KIR-23GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2, and KIR2DL3, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily. KIR2DL3 contains 2 Ig-like C2-type (immunoglobulin-like) domains. KIR2DL3 interacts with ARRB2. KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3, and HLA-Cw7). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.