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Human TSHR Protein, His Tag

Product Information
Catalog Number KMP3416
Product Name Human TSHR Protein, His Tag
Product Description The Human TSHR Protein(KMP3416) is produced in Insect Cells. The target gene encoding the human TSHR (NP_000360.2) (Gly21-Gly413) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name TSHR
Alias Human TSHR Protein, His Tag, TSHR
Molecular Weight 46.1 kDa
Species Human
Size 50ug, 100ug, 200ug
Host Insect Cells
Purity >85% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer 50mM Tris, 150mM NaCl, 10% Glycerol, 1mM TCEP, pH7.5
Purification Affinity purification
Background Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.