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| Catalog Number | KMP3539 |
|---|---|
| Product Name | Human CD3D & CD3E Heterodimer Protein, His Tag |
| Product Description | The Human CD3D & CD3E Heterodimer Protein(KMP3539) is produced in HEK293 Cells. The target gene encoding the extracellular domain (Met1-Ala105) of human CD3D (P04234-1) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; The target gene encoding the extracellular domain (Met1-Asp126) of human CD3E (P07766-1) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the human CD3D/CD3E heterodimer is purified. |
| Molecular Name | CD3D & CD3E Heterodimer |
| Alias | Human CD3D & CD3E Heterodimer Protein, His Tag, CD3D & CD3E Heterodimer |
| Molecular Weight | 22.75 kDa |
| Species | Human |
| Size | 50ug, 100ug, 200ug |
| Host | HEK293 Cells |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, pH7.4 |
| Purification | Affinity purification |
| Background | CD3D (CD3 Delta Subunit Of T-Cell Receptor Complex) is a Protein Coding gene. Diseases associated with CD3D include Immunodeficiency 19 and T-B+ Severe Combined Immunodeficiency Due To Cd3delta/Cd3epsilon/Cd3zeta. Among its related pathways are Immune response NFAT in immune response and TCR Signaling (Qiagen). Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and transmembrane signaling receptor activity. An important paralog of this gene is CD3G. CD3E (CD3 Epsilon Subunit Of T-Cell Receptor Complex) is a Protein Coding gene. Diseases associated with CD3E include Immunodeficiency 18 and T-B+ Severe Combined Immunodeficiency Due To Cd3delta/Cd3epsilon/Cd3zeta. Among its related pathways are Immune response NFAT in immune response and TCR Signaling (Qiagen). Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and obsolete signal transducer activity. An important paralog of this gene is CD3G. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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